The persistence or not of the arteriovenous fistula. A modifiable cardiovascular risk factor.

Authors

Keywords:

Kidney transplant, hemodialysis, arteriovenous fistula

Abstract

Introduction: The arteriovenous fistula constitutes the vascular access of choice to undertake renal replacement therapy with hemodialysis and contributes to patient survival in the purification method. Objective: To determine the impact of the permanence of the arteriovenous fistula on the heart, a quasi-experimental study was designed consisting of two groups of kidney transplant recipients with adequate function; one experimental, with closure of the angioaccess (n=68) and another comparison (n=69), without surgery. In both, clinical, laboratory and echocardiographic variables were compared at two times (final – initial). Results: In the experimental group, improvement was observed in the variables studied compared to the comparison group with statistical significance. Conclusions: The closure of the arteriovenous fistula in patients with a functional kidney transplant represents a modifiable and non-traditional cardiovascular risk factor for cardiovascular dysfunction.

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References

Cruz RE. Fístula arteriovenosa para hemodiálisis en receptores de trasplante renal e implicaciones en el síndrome cardiorrenal tipo 4. Revista Cubana de Medicina. 2022 (Abr-Jun);61(2):e2590.

https://revmedicina.sld.cu/index.php/med/article/view/2590

Brescia MJ, Cimino JE, Appel K, Hurwich BJ. Chronic hemodialysis venipuncture and a surgically created arteriovenous fistula. NEJM [Internet]. 1966 Nov [citado 12/01/2021];275(20):1089-92. Disponible en: https://www.nejm.org/doi/10.1056/NEJM196611172752002?url_ver=Z39.88-

&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed

Basile C, Lomonte C. The arteriovenous fistula is a blessing of God. Nephrol Dial Transplant [Internet]. 2012 Oct [citado 21/01/2021];27(10):3752-6. Disponible en:

https://www.academic.oup.com/ndt/article/27/10/3752/1826757

Hammes M. Hemodynamic and biologic determinates of arteriovenous fistula outcomes in renal failure patients. BioMed Res Int [Internet]. 2015 Oct;2:1-7.

Disponible en:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4606083/pdf/BMRI2015-171674.pdf

Basile C, Vernaglione L, Casucci F, Libutti P, Lisi P, Rossi L, et al. The impact of haemodialysis arteriovenous fistula on haemodynamic parameters of the cardiovascular system. Clin Kidney J [Internet]. 2016 Oct;9(5):729-34. Disponible en:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4606083/pdf/BMRI2015-171674.pdf

Reddy YNV, Obokata M, Dean PG, Melenovsky V, Nath KA, Borlaug BA. Long term cardiovascular changes following creation of arteriovenous fistula in patients with end stage renal disease. Eur Heart J [Internet]. 2017 Jun;38(24):1913-23. Disponible en:

https://www.academic.oup.com/eurheartj/article/38/24/1913/3062803

Yilmaz S, Yetim M, Yilmaz BK, DoganT, Aksoy E, Yuksel N, et al. High hemodialysis vascular access flow and impaired right ventricular function in chronic hemodialysis patients. Indian J Nephrol [Internet]. 2016 Sep;26(5):352-6. Disponible en:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5015514/

Cheung AK, Chang TI, Cushman WC, Furth SL, Hou FF, Ix JH, et al. Excecutive summary of the KDIGO 2021 Clinical Practice Guideline for the Management of Blood Pressure in Chronic Kidney Disease. Kidney Int [Internet]. 2021 Oct;99:559-69.

Disponible en: https://www.kdigo.org/wp-content/uploads/2016/10/KDIGO_BP_Exec_Summary_final.pdf

James PA, Oparil S, Carter BL, Cushman WC, Dennison - Himmelfarb Ch, Handler J, et al. 2014 Evidence - based guideline for the management of high blood pressure in adults: report from the Panel Members Appointed to the Eighth Joint National Committee (JNC 8). JAMA [Internet]. 2014 Oct;311(5):507-20. Disponible en: https://www.jamanetwork.com/journals/jama/fullarticle/1791497

Gluskin E, Tzukert K, Levi IMY, Gotsman O, Sagiv I, Abel R, et al. Ambulatory monitoring unmasks hypertension among kidney transplant patients: single center experience and review of the literature. BMC Nephrology [Internet]. 2019 Jun [citado 6/06/2021];20(284):1-12. Disponible en:

https://www.bmcnephrol.biomedcentral.com/articles/

Einollahi B, Ghahrodi MS. Hemodialysis arteriovenous fistula after transplant. To keep or not to keep? Iran J Kidney Dis [Internet]. 2012 May [citado 12/01/2021];6(3):159-65. Disponible en: http://www.ijkd.org/index.php/ijkd/article/view/853/399

Vanderweckene P, Weekers L, Lancellotti P, Jouret F. Controversies in the management of the haemodialysis - related arteriovenous fistula following kidney transplantation. Clin Kidney J [Internet]. 2018 Jun;11(3):406-12. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6007507/

Aitken E, David K. Arteriovenous fistula and cardiovascular function: the relationship between brain natriuretic peptide, cardiac index and access flow. Kidney Disord Clin Pract [Internet]. 2015 Feb;2(1):15-6. Disponible en: https://www.omicsonline.org/pdfdownload.php?download=open-accesspdfs/arteriovenous-fistulae-and-cardiovascular-function-the-relationshipbetween-brainnaturetic-peptide-cardiac-index-and-access-flow-kdc-1000105.pdf&aid=71733

Ateş Í, Kaya Z, Yegemberdiyev T, Yavuz HA, Demirbaş A, Genç A. Does renal transplantation actually improve heart variability? Biomedical Research [Internet].

Jul;28(3):1081-6. Disponible en:

https://www.alliedacademies.org/articles/does-renal-transplantation-actually-improve-heart-rate-variability.pdf

Rao NN, Stokes MB, Rajwani A, Ullah S, Williams K, King D, et al. Effects of arteriovenous fistula ligation on cardiac structure and function in kidney transplant recipients. Circulation [Internet]. 2019 Jun;139(25):2809-18. Disponible en:

https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.118.038505?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed

Zheng H, Bu S, Song Y, Wang M, Wu J, Chen J. To ligate or not to ligate: A metaanalysis of Cardiac effects and allograft function following arteriovenous fistula closure in renal transplant recipients. Ann Vasc Surg [Internet]. 2020 Feb;63:287-92. Disponible en: https://www.sciencedirect.com/science/article/abs/pii/S0890509619307101?via%3Dih ub

Jeong S, Kwon H, Kim JY, Kim YH, Kwon TW, Lee JB, et al. Effect of arteriovenous access closure and timing on kidney transplant recipients. PLoS ONE [Internet]. 2019 Dec;14(12):e0226309. Disponible en: https://www.journals.plos.org/plosone/article?id=10.1371/journal.pone.0226309

Fraser CD, Grimm JC, Liu RH, Wesson RN, Azar F, Beaulieu RJ, et al. Removal of non - infected arteriovenous fistulae after kidney transplantation is a safe and beneficial management strategy for unused dialysis access. Ann Vasc Surg [Internet]. 2018 Nov;53:128-32. Disponible en: https://www.sciencedirect.com/science/article/abs/pii/S0890509618304394?via%3Dihub

Weekers L, Vanderweckene P, Pottel H, Castanares - Zapatero D, Bonvoisin C, Hamoir E, et al. The closure of arteriovenous fistula in kidney transplant recipients is associated with an acceleration of kidney function decline. Nephrol Dial Transplant [Internet]. 2017 Jan;32(1):196-200. Disponible en: https://www.academic.oup.com/ndt/article/32/1/196/2327318

Zamboli P, Lucà S, Borrelli S, Garofalo C, Liberti ME, Pacilio M, et al. High - flow arteriovenous fistula and heart failure: could the indexation of blood flow rate and echocardiography have a role in the identification of patient at higher risk? J Nephrol [Internet]. 2018 Dec;31(6):975-83. Disponible en: https://www.pubmed.ncbi.nlm.nih.gov/29357085/

Cruz RE, Ramírez JI, González Y, Hernández ME, Hernández OA, Batista R. Repercusión hemodinámica del cierre de la fístula arteriovenosa sobre el corazón derecho en trasplantados renales. Revista Cubana de Medicina [Internet]. 2020 Jul-Sep;59(3):e1371. Disponible en:

https://www.revmedicina.sld.cu/index.php/med/article/view/1371/1318

Letachowicz K, Bardowska K, Królicki T, Kamińska D, Banasik M, Zajdel K, et al. The impact of location and patency of the arteriovenous fistula on quality of life of kidney transplant recipients. Ren Fail [Internet]. 2021 Dec;43(1):113-22. Disponible en: https://www.pubmed.ncbi.nlm.nih.gob/33397180

Letachowicz K, Banasik M, Królicka A, Mazanowska O, Golębiowski T, Augustyniak - Bartsik H, et al. Vascular access perspectives in patients after kidney transplantation. Front. Surg [Internet]. 2021 Apr;8(640986):1-7.

Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8113696/

Jurić A, Zibar L. Arteriovenous fistula after kidney transplantation in University Hospital Centre Osijek. RAD CASA Medical Sciences [Internet]. 2019 Dec;540(48-49):8-14. Disponible en: https://www.pdfs.semanticscholar.org/ee55/7e21c92ae38e25f2eaf281dfc888581289e6.pdf

Hetz P, Pirklbauer M, Müller S, Posch L, Gummerer M, Tiefenthaler M. Prophylactic ligature of AV fistula prevents high output heart failure after kidney transplantation. Am J Nephrol [Internet]. 2020 Jul;51(7):511-9. Disponible en: https://www.karger.com/Article/Abstract/508957

Cheddani L, Liabeuf S, Essig M, Snanoudj R, Jacquelinet C, Kerleau C, et al. Higher mortality risk among kidney transplant recipients then among estimated glomerular fitration rate - matched patients with CKD – preliminary results. Nephrol Dial Transplant [Internet]. 2021 Jan;36(1):176-84.

Disponible en: https://www.pubmed.ncbi.nlm.nih.gov/32162656/

Rabih F, Holden RL, Vasanth P, Pastan SO, Fisher MR, Trammell AW. Effect of pulmonary hypertension on 5 - year outcome of kidney transplantation. Pulmonary Circulation [Internet]. 2022 Jan;12(1):1-10.

Disponible en: https://www.wileyonlinelibrary.com/journal/pul2

Lentine KL, Villines TC, Axelrod D, Karivatne S, Weir MR, Costa SP. Evaluation and management of pulmonary hypertension in kidney transplant candidates and recipients: concepts and controversies.Transplant [Internet]. 2017 Jan;101(1):166-81.

Disponible en: https://www.pubmed.ncbi.nlm.nih.gov/26985742/

Zhao H, Kang Y, Pickle J, Wang J, Han Y. Tricuspid annular plane systolic excursion is dependent on right ventricular volume in addition to function. Echocardiography [Internet]. 2019 Aug;36(8):1459-66. Disponible en: https://www.onlinelibrary.wiley.com/doi/10.1111/echo.14439

Caughey MC, Detwiler RK, Sivak JA, Rose Jones LJ, Kshirsagar AV, Hinderliter AL. Five year outcomes of pulmonary hypertension with and without elevated left atrial pressure in patients evaluated for kidney transplantation. Transplantation [Internet]. 2020 Oct;104(10):2113-9.

Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7316610/

Gonçalves M, Neto M, Pestana N, Resende L, Vieira P, Gomes S.

Echocardiography and cardiovascular risk: The relationship in the renal transplant recipient. Port J Nephrol Hypert [Internet]. 2017 Sep;31(3):167-74.

Disponible en: http://www.bbg01.com/cdn/rsc/spnefro/pjnh/65/n3_2017_pjnh_04.pdf

Stoumpos S, Mark PB. Should we ligate arteriovenous fistulas in asymptomatic patients after kidney transplantation? Circulation [Internet]. 2019 Jun;139(25):2819-21.

Disponible en: https://www.ahajournals.org/

Rao NN, Dundon B, Worthley MI, Faull RJ. The impact of arteriovenous fistula for hemodialysis on the cardiovascular system. Semin Dial [Internet]. 2016 May;29(3):214-21. Disponible en: https://www.onlinelibrary.wiley.com/doi/10.1111/sdi.12459

Cortesi C, Duque JC, Mai S, Martinez L, Dejman A, Vazquez - Padrón R, et al. Assessment of left ventricular mass changes after arteriovenous fistula surgical banding in end - stage renal disease. Saudi J Kidney DisTranspl [Internet]. 2018 Nov-Dec;29(6):1280-9. Disponible en:

https://www.sjkdt.org/article.asp?issn=1319-

;year=2018;volume=29;issue=6;spage=1280;epage=1289;aulast=Cortesi

Movili E, Viola BF, Brunori G, Gaggia P, Camerini C, Zubani R, et al. Long term effects of arteriovenous fistula closure on echocardiographic functional and structural findings in hemodialysis patients: a prospective study. Am J Kidney Dis [Internet]. 2010 Apr;55(4):682-9. Disponible en: https://www.sciencedirect.com/science/article/abs/pii/S0272638609015650?via%3Dih ub

van Duijnhoven EC, Cheriex EC, Tordoir JH, Kooman JP, van Hooff JP. Effect of closure of the arteriovenous fistula on left ventricular dimensions in renal transplant patients. Nephrol Dial Transplant [Internet]. 2001 Feb;16(2):368-72. Disponible en: https://www.google.com/search?client=firefox-bd&q=10.1093%2Fndt%2F16.2.368

Papasotiriou M, Xanthopoulou I, Ntrinias T, Kalliakmani P, Koutsogiannis N, Davlouros P, et al. Impact of arteriovenous fistula on cardiac size and function in kidney transplant recipients: A retrospective evaluation of 5 - year echocardiographic outcome. Exp Clin Transplant [Internet]. 2019 Oct;17(5):619-26. Disponible en: https://www.pubmed.ncbi.nlm.nih.gov/31180298/

Rao NN, Stokes MB, Rajwani A, Ullah S, Williams K, King D, et al. Effects of arteriovenous fistula ligation on cardiac structure and function in kidney transplant recipients. Circulation [Internet]. 2019 Jun;139(25):2809-18. Disponible en:

https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.118.038505?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed

Saleh MA, El Kilany WM, Keddis VW, El Said TW. Effect of high flow arteriovenous fistula on cardiac function in hemodialysis patients. Egypt Heart J [Internet]. 2018 Dec;70:337-41. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6303531/

Zahra SA, Choudhury RY, Basharat K, Tran T, Begun M, Fatemeh AA, et al. Translational sciences in cardiac failure secondary to arteriovenous fistula in hemodialysis patients. Ann Vasc Surg [Internet]. 2021 Feb;S08905096(21):00109-16. Disponible en:

https://www.sciencedirect.com/science/article/abs/pii/S0890509621001096?via%3Dih ub

Reddy YNV, Melenovsky V, Redfield MM, Nishimura RA, Borlaug BA. High output heart failure. A 15 - year experience. J Am Coll Cardiol [Internet]. 2016 Aug;68(5):473-82.

Disponible en: https://www.linkinghub.elsevier.com/retrieve/pii/S0735-1097(16)33269-7

Published

2023-11-25

How to Cite

1.
Cruz Abascal RE, Gutiérrez Gutiérrez C. The persistence or not of the arteriovenous fistula. A modifiable cardiovascular risk factor. Rev. nefrol. cuban. [Internet]. 2023 Nov. 25 [cited 2024 Dec. 3];1(1). Available from: https://revnefrologia.sld.cu/index.php/nefrologia/article/view/16

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